Hospital empirical antimicrobial therapy for adults
Oral thrush
Before proceeding, read the empirical therapy - general notes section.
Notes
Send scrapings for culture
Likely organism
Candida albicans
1st choice antibiotic
Nystatin oral suspension, use 1mL as a mouthwash (then swallow) four times daily, usually for 7 days
Continue for 2 days after lesions have resolved
Immunocompromised: Fluconazole 100mg orally once daily for 7-14 days
2nd choice antibiotic
Miconazole oral gel 5-10mL four times daily after food for 7 days (continue for 2 days after lesions have resolved).
Note: interaction with warfarin - enhances anticoagulant effect of coumarins (miconazole oral gel and possibly other topical formulations absorbed).
Back to antimicrobial empirical therapy for ENT infection webpage, also see 12.3.2.