15.1.6 Drugs for reversal of neuromuscular blockade
The drugs in this section should only be administered by, or under direct supervision of personnel experienced in their use.
Neostigmine speeds the offset of non-depolarising muscle relaxant drugs. Its onset of action is within one minute of intravenous administration. Atropine or glycopyrronium should be given with this agent to counteract muscarinic effects.
Sugammadex (injection, Bridion®) is available for restricted use for the immediate reversal of profound rocuronium-induced neuromuscular blockade in adults only [SMC 527/09]. Sugammadex is used mainly for the rapid reversal of neuromuscular blockade in an emergency.
Available for use under protocol for all theatres and intensive care units including Dr Gray's.